Genetically Modified Mouse Laboratory (GMML)

 

GMML
GMML

  

  • Random integration via pronuclear micro-injection

  • Targeted integration via pronuclear micro-injection
    • Zinc Finger (ZFn)Technology
    • Insert markers to track cellular sites of expression
    • High throughput generation of multiple strains of Knockout mice through the use of numerous homologous recombination point mutation inserts
  •  Maximum weekly throughput capabilities
    • Process up to 1000-2000 fertilized embryos
    • Generate 50-65 pregnant females
    • Produce up to 650 offspring, yielding 30-130 genetically modified mice
 

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